In this study, we present an example of a functionally relevant coding sequence variation, which, as we show here, confers risk for large artery atherosclerotic stroke.
Our results indicate that the interplay between AAT, NE, and lipoprotein particles is modulated by the gate region around position 213 in AAT, far away from the unaltered reactive center loop (357–360).
Leonard and Kim agreed that the burger itself was “just OK.” Washington resident Chaim Schramm, a vegetarian, said the burger did not make the cut among the meat substitute-based burgers he has eaten.
Common single-amino acid variations of proteins are traditionally regarded as functionally neutral polymorphisms because these substitutions are mostly located outside functionally relevant surfaces.
About a quarter of ischemic stroke cases are caused by large artery atherosclerotic stroke (LAS) (3, 4).
Atherosclerosis is a chronic inflammatory condition that involves a number of well-characterized steps.
Kim said her logic behind choosing the Impossible Burger night was simple.